Date of Award
Dr. Danielle Kara
Currently, there is a need for a cost-effective and more efficient option for gout diagnosis. Traditionally, gout is diagnosed by the presence of monosodium urate in blood or synovial fluid. The purpose of this research is to quantify the magneto-optical properties of monosodium urate crystals using a magneto-optical device (MOD). Characterization of these magnetic and optical properties is achieved through measuring the initial light intensity and the transmitted light intensity of a laser shone through a sample of monosodium urate with or without a static magnetic field. The comparison of the transmitted intensity through a solution of MSU crystals with a static magnetic field on or off allows for the analysis of the average extinction cross-section a. Using our theoretical model under the simplifying assumption that absorption is dominant, we determined that ax= 0.0127 cm3 /µg and we determined Uz using two different relationships which gave values of 7 x 10-4 cm3 /µg and 0.0033 cm3 /µg. Due to the apparent difference in our calculations of Uz, we determined that the extinction cross section for MSU crystals relies on both scattering and absorption interactions.
Marino, Victoria, "Examining the Optical Properties of Monosodium Urate for the Detection of Gout Using a Magneto-Optical Device (MOD)" (2022). Senior Honors Projects. 131.
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